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BSc Tuition > Learn BSc Tuition > Which is the receptor host cell in HIV infection?
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Which is the receptor host cell in HIV infection?

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HIV enters macrophages and CD4-positive T cells (CD4 is a glycoprotein receptor found on cells) by the adsorption of glycoproteins on its surface to receptors on the target cell, followed by fusion of the viral envelope with the cell membrane and the release of the HIV capsid into the cell .Two glycoproteins...
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HIV enters macrophages and CD4-positive T cells (CD4 is a glycoprotein receptor found on cells) by the adsorption of glycoproteins on its surface to receptors on the target cell, followed by fusion of the viral envelope with the cell membrane and the release of the HIV capsid into the cell .Two glycoproteins make up env and these protrude from the virion. The cap of the protein is called gp120 and the stem is gp41. For HIV to enter a host cell, it must first use gp120 to attach to a CD4 receptor. The CD4 receptor is found on CD4 T-cells and macrophages. read less
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