Node.js simplifies development by exposing a single-threaded programming model, while internally managing multiple POSIX threads for I/O operations like file access, DNS lookups, and network requests.
When Node.js receives an I/O request, it delegates the operation to a thread. Once the operation completes, the result is added to the event queue. The event loop continually checks this queue and pushes results to the execution stack, provided it is empty.